The Egypt Genome Project

• Mohamed A. Elmonem  ORCID: orcid.org/0000-0002-3154-19481,2,
• Neveen A. Soliman  ORCID: orcid.org/0000-0002-8942-19731,3,
• Ahmed Moustafa1,4,
• Yehia Z. Gad  ORCID: orcid.org/0000-0002-8432-45415,6,
• Wael A. Hassan1,
• Tarek Taha1,
• Gina El-Feky7,
• Mahmoud Sakr7 &
• …
• Khaled Amer  ORCID: orcid.org/0000-0001-6896-94491 

Nature Genetics (2024)Cite this article

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The recently launched Egyptian Genome Project aims to sequence genomic variants of 100,000 apparently healthy Egyptian adults, with around 8,000 individuals suspected to have a genetic disease, as well as 200 ancient Egyptian mummies. The project will provide the first comprehensive genomic dataset from Egypt and North Africa.

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References

1. Lander, E. S. et al. Nature 409, 860-1921 (2001).

   Article  CAS  PubMed  Google Scholar 

2. Karczewski, K. J. et al. Nature 581, 434-443 (2020).

   Article  CAS  PubMed  PubMed Central  Google Scholar 

3. Taliun, D. et al. Nature 590, 290-299 (2021).

   Article  CAS  PubMed  PubMed Central  Google Scholar 

4. Sakaue, S. et al. Nat. Med. 26, 542-548 (2020).

   Article  CAS  PubMed  Google Scholar 

5. Pearce, C. et al. Genet. Med. 21, 2667-2675 (2019).

   Article  PubMed  Google Scholar 

6. Pagani, L. et al. Am. J. Hum. Genet. 96, 986-991 (2015).

   Article  CAS  PubMed  PubMed Central  Google Scholar 

7. Hawass, Z. et al. JAMA 303, 638-647 (2010).

   Article  CAS  PubMed  Google Scholar 

8. Gad, Y. Z. et al. Hum. Mol. Genet. 30, R24-R28 (2021).

   Article  CAS  PubMed  Google Scholar 

9. Roberts, C. & Ingham, S. Int. J. Osteoarchaeol. 18, 600-613 (2008).

   Article  Google Scholar 

10. Rohland, N. et al. Nat. Protoc. 13, 2447-2461 (2018).

    Article  CAS  PubMed  Google Scholar 

11. Fatumo, S. et al. Nat. Med. 28, 243-250 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

12. Zink, A. R. et al. J. Clin. Microbiol. 41, 359-367 (2003).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

13. Lalremruata, A. et al. PLoS ONE 8, e60307 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

14. Kloos, H. & David, R. Hum. Ecol. Rev. 9, 14-25 (2002).

    Google Scholar 

15. Kumar, R. & Dhanda, S. K. Bioinformation 16, 297-300 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

1. Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo, Egypt

   Mohamed A. Elmonem, Neveen A. Soliman, Ahmed Moustafa, Wael A. Hassan, Tarek Taha & Khaled Amer

2. Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt

   Mohamed A. Elmonem

3. Department of Pediatrics, Center for Pediatric Nephrology and Transplantation (CPNT), Faculty of Medicine, Cairo University, Cairo, Egypt

   Neveen A. Soliman

4. Departments of Biology and Bioinformatics and Integrative Genomics Laboratory, American University in Cairo, Cairo, Egypt

   Ahmed Moustafa

5. Department of Medical Molecular Genetics, Human Genetics and Genome Research Institute, National Research Center, Cairo, Egypt

   Yehia Z. Gad

6. Ancient DNA laboratory, National Museum of Egyptian Civilization, Cairo, Egypt

   Yehia Z. Gad

7. Academy of Scientific Research and Technology, Cairo, Egypt

   Gina El-Feky & Mahmoud Sakr

Corresponding authors

Correspondence to Mohamed A. Elmonem or Neveen A. Soliman.

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Competing interests

The authors declare no competing interests.

Peer review

Peer review information

Nature Genetics thanks Mark Caulfield for their contribution to the peer review of this work.

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Cite this article

Elmonem, M.A., Soliman, N.A., Moustafa, A. et al. The Egypt Genome Project. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01739-1

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• Published: 29 April 2024

• DOI: https://doi.org/10.1038/s41588-024-01739-1